Bismuth Subsalicylate: Overview, Questions, Preparation

Alcohols, Phenols and Ethers

Updated on Apr 17, 2021 07:00 IST

What is Bismuth Subsalicylate?

Bismuth Subsalicylate is an antacid recognised under the brand name of Pepto-Bismol with the chemical formula of C7H5BiO4. Bismuth Subsalicylate is an insoluble salt commonly used for stomach issues, indigestion, and nausea. It is also common for the treatment of syphilis. It takes time and slowly gets absorbed into the body but is considered very effective. It is also proven helpful for patients with inflammatory issues. 

 Acetylation of Salicylic Acid produces Aspirin

Acetylation of Salicylic Acid produces Aspirin

It is a white textured powder that has no rancid odour. It is also highly soluble in alkali, but partially soluble in water or alcohol. Some of the other famous names of Bismuth Subsalicylate are salicylic acid and sic bismuth subsalicylate.

Properties of Bismuth Subsalicylate

Chemical Formula

C7H5BiO4

Molar Mass

362.093 g/mol

Density

0.43g/cm3

Melting Point

350 °C

Boiling Point

336.3°C

Trade Name

Pepto-Bismol

Chemical Properties of Bismuth Subsalicylate

  • Hydrochloric acid and bismuth subsalicylate react with each other and form bismuth chloride and 3,5-Dihydroxybenzoic acid. The chemical reaction is as follows:

C7H5BiO4 + HCl → C7H6O4 + BiCl

  • It produces microparticles around while reacting, which later gets decomposed by the boiling point of water, in the presence of alkali particles. It is highly soluble in alkali.

Uses of Bismuth Subsalicylate

  1. Bismuth subsalicylate is used as an antifungal agent, particularly in Tobacco seedlings
  2. Bismuth Subsalicylate is most commonly used for treating stomach issues such as indigestion and other inflammatory conditions
  3. It can also be used for the treatment of diarrhoea in animals (be it small or large)
  4. It is used for the treatment of syphilis, and also, for patients who are sensitive or allergic to penicillin

Direction to Use Bismuth Subsalicylate

  • 30 ml every 30 minutes is usually advised for patients suffering from stomach issues, indigestion, and nausea
  • 30 ml every 30 minutes or two doses in an hour are recommended for diarrhoea patients
  • It is advised not to take more than eight doses, as the excessive amount can do more harm than good
  • For children, it is highly advisable to go and consult a doctor, as children are more sensitive to the medication, and it can cause allergies

Bismuth Subsalicylate in Class 12

For the year 2021, the chapter of Alcohol, Phenols & Ethers holds a weightage of 6 marks, which includes one short question (3 marks), one very short question (2 marks) and one objective question (1 mark).

Illustrated Examples

 Q. How can Salicylic Acid (Bismuth Subsalicylate) be used in the production of Aspirin? Illustrate with a chemical process.

Answer – The following process illustrates the production of Aspirin with the help of Salicylic Acid undergoing a process of Acetylation.

Salicylic Acid in Aspirin production

FAQs regarding Bismuth Subsalicylate

Q. Why is Bismuth Subsalicylate so effective?

A.  Bismuth Subsalicylate is so effective because it kills the excessive acids in the body slowly and alleviates the body pain. Patients can either consume it as a tablet or in liquid form.

Q. What is the chemical formula of Bismuth Subsalicylate?

A.  The chemical formula of Bismuth Subsalicylate is C 7 H 5 BiO 4.

Q. What is Bismuth Subsalicylate most famous for?

A.  Bismuth Subsalicylate is most famous for the treatment of syphilis and stomach issues such as indigestion.

Q. Is Bismuth Subsalicylate soluble?

A.  Bismuth Subsalicylate is not fully soluble in water or alcohol; however, it is highly soluble in alkali.

Q. Does Bismuth Subsalicylate kill bacteria?

A.  Yes, the Bismuth concentration kills bacteria. However, this alone is not effective enough to kill serious bacteria. 

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