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Introduction to Bioconductor 
offered by Harvard University

Introduction to Bioconductor
 at 
Harvard University 
Overview

The structure, annotation, normalization, and interpretation of genome scale assays.

Duration

4 weeks

Total fee

18,186

Mode of learning

Online

Difficulty level

Intermediate

Official Website

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Course Level

UG Certificate

Introduction to Bioconductor
 at 
Harvard University 
Highlights

  • Earn a certificate after completion of the course
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Introduction to Bioconductor
 at 
Harvard University 
Course details

What are the course deliverables?
  • What we measure with high-throughput technologies and why
  • Introduction to high-throughput technologies: Next generation sequencing and Microarrays
  • Preprocessing and normalization
  • The Bioconductor Genomic Ranges utilities
  • Genomic annotation
More about this course
  • We begin with an introduction to the relevant biology, explaining what we measure and why
  • Then we focus on the two main measurement technologies: next generation sequencing and microarrays
  • We then move on to describing how raw data and experimental information are imported into R and how we use Bioconductor classes to organize these data, whether generated locally, or harvested from public repositories or institutional archives
  • Genomic features are generally identified using intervals in genomic coordinates, and highly efficient algorithms for computing with genomic intervals will be examined in detail
  • Statistical methods for testing gene-centric or pathway-centric hypotheses with genome-scale data are found in packages such as limma, some of these techniques will be illustrated in lectures and labs.
  • Given the diversity in educational background of our students we have divided the series into seven parts
  • You can take the entire series or individual courses that interest you
  • If you are a statistician you should consider skipping the first two or three courses; similarly, if you are a biologist you should consider skipping some of the introductory biology lectures. Note that the statistics and programming aspects of the class ramp up in difficulty relatively quickly across the first three courses. By the third course we'll be teaching advanced statistical concepts such as hierarchical models and by the fourth advanced software engineering skills, such as parallel computing and reproducible research concepts.
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Introduction to Bioconductor
 at 
Harvard University 
Curriculum

Data Science, Biostatistics, Data Analysis, R, Statistics, Biology

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Introduction to Bioconductor
 at 
Harvard University 
Faculty details

Rafael Irizarry
Designation : Professor of Biostatistics, T.H. Chan School of Public Health
Michael Love
Designation : Assistant Professor, Departments of Biostatistics and Genetics, UNC Gillings School of Global Public Health
Vincent Carey
Designation : Professor of Medicine (Biostatistics) in the Channing Division of Network Medicine, Brigham and Women’s Hospital, Harvard Medical School

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Introduction to Bioconductor
 at 
Harvard University 
Contact Information

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