Vanderbilt University - Case Studies in Personalized Medicine
- Offered byCoursera
Case Studies in Personalized Medicine at Coursera Overview
Duration | 18 hours |
Start from | Start Now |
Total fee | Free |
Mode of learning | Online |
Official Website | Explore Free Course  |
Credential | Certificate |
Case Studies in Personalized Medicine at Coursera Highlights
- Shareable Certificate Earn a Certificate upon completion
- 100% online Start instantly and learn at your own schedule.
- Flexible deadlines Reset deadlines in accordance to your schedule.
- Approx. 18 hours to complete
- English Subtitles: French, Portuguese (European), Russian, English, Spanish
Case Studies in Personalized Medicine at Coursera Course details
- Learn how advances in biomedicine hold the potential to revolutionize drug development, drug treatments, and disease prevention: where are we now, and what does the future hold? This course will present short primers in genetics and mechanisms underlying variability in drug responses. A series of case studies will be used to illustrate principles of how genetics are being brought to bear on refining diagnoses and on personalizing treatment in rare and common diseases. The ethical and operational issues around how to implement large scale genomic sequencing in clinical practice will be addressed.
- After completing this course, learners will understand
- 1. The ways in which genetic variants can contribute to human disease susceptibility
- 2. How to choose among drug therapies based on genetic factors
- 3. That the functional consequences of the vast majority of genetic variants discovered by modern sequencing are unknown.
- This course is targeted primarily at physicians 5+ years out of training. Other healthcare providers, medical/health sciences students, and members of the public may also be interested.
- Course launches January 15, 2016.
- * The information presented in ?Case Studies in Personalized Medicine? is offered for educational and informational purposes only, and should not be construed as personal medical advice. If you have questions or concerns about a medical matter, please consult your doctor or other professional healthcare provider.
Case Studies in Personalized Medicine at Coursera Curriculum
UNIT 1: INTRODUCTION TO PERSONALIZED MEDICINE
A welcome message from Dr. Roden
Introduction to Personalized Medicine
Genetics Definitions, Part I
Genetics Definitions, Part II & Types of Genetic Variants
Data Analysis, Part I: What is a Good Study?
Data Analysis, Part II: What is a Good Test?
Introduction to Drug Therapy and General Mechanisms Underlying Variability in Drug Responses
Variability in Drug Therapy
Drug Metabolism & Transport
Genetic Variability in Drug-Handling Molecules
**Inside VUMC: The Promise of Personalized Medicine
About this course
Introduction to Personalized Medicine
UNIT 2: STUDYING GENETIC VARIATION
Family History and Inheritance Patterns
Ancestry: Genetic Variation Across Generations and Geography
Finding Disease-Associated Genes: Linkage
**Inside VUMC: From Phenotype to Genotype and Back: Studying Heart Disease in Families
Genome-Wide Association
Sequencing
**Inside VUMC: History of Sequencing Technologies
Studying Genetic Variation
UNIT 3: CASE STUDIES IN PERSONALIZED MEDICINE, PART 1
From rare to common disease: familial hypercholesterolemia
Using Genomics to Find New Drug Targets: Familial Hypercholesterolemia
Muscle Pains During Statin Therapy (Myopathy)
HLA-Mediated Immune Reactions (Skin Rash)
Long QT Syndromes, Part 1
Long QT Syndromes, Part 2
**Inside VUMC: Studying Cardiac Arrhythmias in Cells
A Second Heart Attack a Month After a First
Headache During Venlafaxine (Antidepressant)
Respiratory Arrest After Tonsillectomy
A Bleeding Complication 5 Days After Starting Warfarin
**Inside VUMC: Genotyping
Drug Metabolism and Variable Drug Responses ? Four More Examples
Case Studies, Part I
UNIT 4: CASE STUDIES IN PERSONALIZED MEDICINE, PART 2
Cystic Fibrosis
Marfan Syndrome
A Case of Idiopathic Heart Failure
Personalizing Care in Neuropsychiatric Disease
Personalizing Care in Diabetes
Genomics to Subtype Cancer
A Family Member With Breast Cancer
A Family Member With Colon Cancer
**Inside VUMC: Organizing Infrastructure to Support Genetic Testing Decisions
Case Studies, Part II
UNIT 5: PERSONALIZED MEDICINE IN A SYSTEM OF CARE
Where We Are Now
Where We Are Going
**Inside VUMC: Using iPSCs: Drug Discovery and Drug Efficacy
**Inside VUMC: Generating iPSCs
Electronic Medical Records & The Learning Healthcare System (Discovery)
Using Electronic Records to Personalize Care (Delivery)
**Inside VUMC: Using the EMR to Ascertain Patients for Genetic Studies
**Inside VUMC: Biobanking & DNA Extraction at BioVU
**Inside VUMC: Personalized Medicine is a Team Sport
Personalized Medicine in a System of Care
FINAL REFLECTION ACTIVITY
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