Rice University - Fundamentals of Immunology: T Cells and Signaling
- Offered byCoursera
Fundamentals of Immunology: T Cells and Signaling at Coursera Overview
Duration | 26 hours |
Start from | Start Now |
Total fee | Free |
Mode of learning | Online |
Difficulty level | Intermediate |
Official Website | Explore Free Course  |
Credential | Certificate |
Fundamentals of Immunology: T Cells and Signaling at Coursera Highlights
- Shareable Certificate Earn a Certificate upon completion
- 100% online Start instantly and learn at your own schedule.
- Course 2 of 4 in the Fundamentals of Immunology Specialization
- Flexible deadlines Reset deadlines in accordance to your schedule.
- Intermediate Level
- Approx. 26 hours to complete
- English Subtitles: Arabic, French, Portuguese (European), Italian, Vietnamese, German, Russian, English, Spanish
Fundamentals of Immunology: T Cells and Signaling at Coursera Course details
- Course 2 of a three course specialization called Fundamentals of Immunology. Each course in the specialization presents material that builds on the previous course's material.
- This is the second half of the journey through the defenses your body uses to keep you healthy. In the first part we learned about innate immunity and B cell function. The second part covers T cell function and coordination of the immune response.
- Fundamentals of Immunology: T cells and Signaling builds on the first course to describe the functions of Complement, MHC presentation to T cells, T cell development and signaling. The early lectures survey cells, tissues and organs using metaphors, cartoons and models to improve understanding and retention. This course includes the structure of both MHC proteins and T cell receptors and the sources of variation. The course provides animations of gene rearrangement, developmental processes and signal cascades. Testing employs multiple choice questions testing facts, concepts, and application of principles. Questions may refer to diagrams, drawing and photographs used in lecture and reproduced in the outline.
- What You?ll Learn:
- How complement uses adaptive and innate triggers to target pathogens. The detailed structure and coding of MHC proteins and both alpha-beta and gamma delta receptors and how these proteins interact to initiate an adaptive immune response. The basics of signaling, and the varieties of external receipt and internal activation pathways. We bine the process of putting together how signals and crosstalk control the activity of the immune system.
Fundamentals of Immunology: T Cells and Signaling at Coursera Curriculum
Complement
Welcome
Overview and Terminology
Activation of MAC
Classical Pathway
Alternative Pathway
Lectin Pathway
Endgame and Consequences
Course Study Guide
Pre-Course Survey
Lesson 1
Lesson 2
Lesson 3
Lesson 4
Lesson 5
Lesson 6
Lecture 1 Practice Quiz
Lecture 1 Quiz
The Major Histocompatability Complex
MHC Genes
MHC Haplotypes
Inbreeding
MHC Protein Structure
Specifics of Peptide Binding
MHC Genetic Expression
Non-Classical Alleles
MHC and Disease
Lesson 1
Lesson 2
Lesson 3
Lesson 4
Lesson 5
Lesson 6
Lesson 7
Lesson 8
Lecture 2 Practice Quiz
Lecture 2 Quiz
Antigen Processing and Presentation
T Cell Antigen Recognition
Self-MHC Restriction
The Cytosolic Pathway
The Exogenous Pathway
Variations
Comparisons and Questions
Lesson 1
Lesson 2
Lesson 3
Lesson 4
Lesson 5
Lesson 6
Lecture 3 Quiz
Lecture 3 Practice Quiz
T-Cell Receptors
Early Work
Structure and Roles
T-cell Receptor Genes
Gene Rearrangement: ?? genes
Gene Rearrangement: ?? genes
Diversity and its Constraints
The TCR Receptor Complex
Alloreactivity
Lesson 1
Lesson 2
Lesson 3
Lesson 4
Lesson 5
Lesson 6
Lesson 7
Lesson 8
Lecture 4 Quiz
T-Cell Development
Into the Thymus
Double Negative Transitions
Double Positive Event: Positive Selection
Negative Selection
CD 4+ Varieties
Activation
Lesson 1
Lesson 2
Lesson 3
Lesson 4
Lesson 5
Lesson 6
Lecture 5 Quiz
Cytokines and Signaling
Information Transfer
Fundamental Signals
Contributory Signals
Common Themes in Signaling
Signaling and TH Subsets
Determining the TH Subsets
Clinical Applications
Lesson 1
Lesson 2
Lesson 3
Lesson 4
Lesson 5
Lesson 6
Lesson 7
Lecture 6 Quiz
Final
Farewell
End-of-Course Survey
Final
Fundamentals of Immunology: T Cells and Signaling at Coursera Admission Process
Important Dates
Other courses offered by Coursera
Student Forum
Anything you would want to ask experts?
Useful Links
Know more about Coursera
Know more about Programs
- Medical Courses
- Public Health & Management
- Hospital Management Course
- Medical Transcription
- Perfusion Technology
- Diabetology
- Forensic Medical Science
- Dialysis Technology
- Cardiovascular Technology
- Cath Lab Technology
- BSc Operation Theatre Technology
- BSc in Perfusion Technology
- Physician Assistant
- BSc Physician Assistant
- BSc in Respiratory Care Technology