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University of Exeter - Genomic Medicine: Transforming Patient Care in Diabetes 

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Genomic Medicine: Transforming Patient Care in Diabetes
 at 
FutureLearn 
Overview

Duration

4 weeks

Total fee

2,763

Mode of learning

Online

Official Website

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Credential

Certificate

Genomic Medicine: Transforming Patient Care in Diabetes
 at 
FutureLearn 
Highlights

  • Duration 4 weeks
  • Weekly study 2 hours
  • 100% online Learn at your own pace
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Genomic Medicine: Transforming Patient Care in Diabetes
 at 
FutureLearn 
Course details

Skills you will learn
More about this course
  • There have been huge advances in the field of genetics in the last 10 years since the sequencing of the first human genome in 2003. It is now possible to analyse all 20,000 human genes in a single experiment, rather than focussing on one gene at a time. We are in the genomics era.
  • This free online course will introduce the topic of genomics, using the University of Exeter's research expertise in diabetes, to illustrate the clinical application of current genomics knowledge.
  • We will use patient experiences to discuss the impact and value of a genetic diagnosis for diabetes for patients, their families and the clinicians responsible for their care. You will learn about the value of understanding the underlying pathological mechanism of a disease, to enable the progression from genomic testing to improvements in clinical care.
  • You will learn about: the different modes of inheritance for diabetes, including polygenic, monogenic, mitochondrial and epigenetic; the molecular basis of these inheritance patterns; and how this relates to risk for individuals, families and populations.
  • You will be taken through the process of discovering novel genetic mutations in the genome, including intergenic regions, previously thought to play a minor role in gene function. This will include thinking about the pattern of inheritance, to design a strategy for gene discovery, through to the latest laboratory techniques used for genomic sequencing.
  • There will also be an introduction to the bioinformatics resources and techniques used to interpret the wealth of genomic data generated by the techniques described.
  • We won't be able to join the discussions ourselves, so we hope that the course will be one that develops a strong learning community. We encourage you to participate fully in discussions, to support other learners and to share knowledge where possible, and hope that you will enjoy interacting with and learning from each other in this way.
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Genomic Medicine: Transforming Patient Care in Diabetes
 at 
FutureLearn 
Curriculum

Changing lives: why do genomics testing?

Neonatal diabetes: an exemplar for genomic medicine

Common and rare monogenic subtypes of diabetes

Diagnosis and risk

Multifactorial diabetes

Identifying patients with monogenic diabetes

Inheritance patterns for monogenic diabetes

Strategies for genomic testing

Which patients can benefit from genomic tests?

How do we test for monogenic diabetes? Part A ? in the laboratory

How do we test for monogenic diabetes? Part B ? interpreting the result

Genetic testing for relatives

Finding new disease genes

Using next generation sequencing technology to diagnose monogenic diabetes

Discovering the cause of a rare syndrome with new genomic sequencing technology

Scientific, ethical, social and legal issues

Course wrap up

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Genomic Medicine: Transforming Patient Care in Diabetes
 at 
FutureLearn 

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