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Getting started in cryo-EM 

  • Offered byCaltech

Getting started in cryo-EM
 at 
Caltech 
Overview

Learn foundational principles and practical techniques involved in this advanced imaging method

Duration

21 hours

Mode of learning

Online

Official Website

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Credential

Certificate

Getting started in cryo-EM
 at 
Caltech 
Highlights

  • Earn a certificate after completion of the course
  • Financial aid available
  • Assessments and Quizzes for practice
Details Icon

Getting started in cryo-EM
 at 
Caltech 
Course details

More about this course
  • This course covers the fundamental principles underlying cryo-electron microscopy (cryo-EM) starting with the basic anatomy of electron microscopes, an introduction to Fourier transforms, and the principles of image formation
  • This course emphasizes concepts rather than mathematical details, taught through numerous drawings and example images

Getting started in cryo-EM
 at 
Caltech 
Curriculum

Welcome

Introduction to the Course

Description of Parts

Currents, Coils, Knobs and Names: Basic anatomy of the electron microscope

Introduction: Basic Anatomy of the EM

Electron Guns

Fourier Transforms and Reciprocal Space for Beginners

Introduction: Fourier Transforms for Beginnners

1-D Sine Waves and their Sums

Image Formation

Introduction: Image Formation

Amplitude and Phase Contrast

Fundamental Challenges in Biological EM

Introduction: Fundamental Challenges in Biological EM

Sample Prep - Room Temperature Methods

Single Particle Analysis

Special sample prep issues

Data collection (imaging)

Tomography

Introduction: Tomography

Tomography Data Collection and Reconstruction

2-D Crystallography

Introduction: 2-D Crystallography and Sample Prep

FT of a 2-D Crystal

Faculty Icon

Getting started in cryo-EM
 at 
Caltech 
Faculty details

Grant J. Jensen

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Getting started in cryo-EM
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Caltech 

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