DTU - Introduction to Industrial Bioprocess Development
- Offered byCoursera
Introduction to Industrial Bioprocess Development at Coursera Overview
Duration | 15 hours |
Start from | Start Now |
Total fee | Free |
Mode of learning | Online |
Difficulty level | Beginner |
Official Website | Explore Free Course |
Credential | Certificate |
Introduction to Industrial Bioprocess Development at Coursera Highlights
- Earn a Certificate upon completion
Coursera Labs
Flexible Schedule
Introduction to Industrial Bioprocess Development at Coursera Course details
- The course begins with a brief description of some basic properties of microorganisms and general aspects related to their use in bioprocesses at industrial scale
- The course includes a group of lectures dedicated to some stages that precede fermentation; specifically, media formulation, sterilization, preservation of microorganisms and inoculum preparation
- The main characteristics of predominant types of industrial bioreactors along with process parameters that need to be controlled in stirred tank reactors are also covered in one of the modules of the course
- Since the expansion of a bioprocess from a lab scale to an industrial scale is of considerable importance, an additional lecture dedicated to this topic is presented. The last part of the course provides a general overview of downstream processing, addressing processes used for the removal of cells from the culture medium, methods for the disruption of cells, and isolation of the target bioproduct
- By the end of the course, learner should:
- Be able to identify the fundamental difference between the two basic cell types: eukaryotic and prokaryotic cells
- Distinguish the main steps of the brewing process
- Identify some important steps in recombinant protein production
- Define the different stages of the industrial production of bioethanol
- Distinguish the main characteristics of the three fermentation modes: batch, continuous and fed-batch
- Define important parameters of the continuous fermentation mode
- Identify bioprocesses where fed-batch fermenters are used and for how long can a fed-batch process be run
- Identify how defined and undefined fermentation media are formulated
- Discuss the role that key components of culture media play in bioconversion processes
- Recognize the importance in avoiding microbial contamination
- Describe chemical and physical sterilization methods
- Distinguish the main characteristics of common techniques of cell preservation
- Recognize factors that are commonly considered to obtain an inoculum suitable for fermentation at industrial scale
Introduction to Industrial Bioprocess Development at Coursera Curriculum
Module 1 - Fundamentals of Microbial Bioreaction Design
Welcome lecture
Properties of microorganisms
The development of fermentation - Part 1
The development of fermentation - Part 2
The development of fermentation - Part 3
About the Course Team
Suggested literature
Fundamentals of Microbial Bioreaction Design - Graded Quiz
Module 2 - Mass Balances and Kinetics
Batch
Chemostat
Fed-batch
Suggested literature
Mass Balances and Kinetics - Graded Quiz
Module 3 - Upstream Processing
Medium formulation
Sterilization
Preservation of microorganisms
Inoculum development
Suggested literature
Upstream Processing - Graded Quiz
Module 4 - Bioreactor Engineering
Types of bioreactors
Parameters affecting bioprocesses in Stirred Tank Reactors
Bioprocess scale-up
Suggested literature
Bioreactor Engineering - Graded Quiz
Module 5 - Downstream Processing
Product recovery
Primary isolation
Case study
Suggested literature
Downstream Processing - Graded Quiz
Introduction to Industrial Bioprocess Development at Coursera Admission Process
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