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NYU - Introduction to the Multiphase Optimization Strategy (MOST) 

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Introduction to the Multiphase Optimization Strategy (MOST)
 at 
Coursera 
Overview

Duration

18 hours

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Total fee

Free

Mode of learning

Online

Official Website

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Credential

Certificate

Introduction to the Multiphase Optimization Strategy (MOST)
 at 
Coursera 
Highlights

  • Earn a Certificate upon completion from New York University
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Introduction to the Multiphase Optimization Strategy (MOST)
 at 
Coursera 
Course details

Skills you will learn
More about this course
  • This course is aimed at intervention scientists working in any area--including public health, education, criminal justice, and others-interested in learning about an innovative framework for conducting intervention research
  • This course will show you how to use the multiphase optimization strategy (MOST) to: streamline interventions by eliminating inactive components; identify the combination of components that offers the greatest effectiveness without exceeding a defined implementation budget; develop interventions for immediate scalability; look inside the "black box" to understand which intervention components work and which do not; and improve interventions programmatically over time
  • In this course you will relate the MOST framework to your research objectives; learn how MOST differs from the standard approach to intervention development and evaluation; learn how to complete the preparation and optimization phases of MOST; and become familiar with rigorous and highly efficient experimental designs that will enable you to examine the performance of individual intervention components
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Introduction to the Multiphase Optimization Strategy (MOST)
 at 
Coursera 
Curriculum

Week 1 - MOST is a different way of thinking

Introduction to this course

Definitions of key concepts, Part 1

Definitions of key concepts, Part 2

What knowledge can and cannot be obtained from an RCT

Comparison of the classical treatment package and engineering approaches

The concept of optimization

The three phases of MOST

Why MOST is a different way of thinking

Review of Module 1

Course Review Form

Reading for ALL OF Module 1

Week 2 - The preparation phase: Laying the foundation for successful optimization

Basics of the Conceptual Model

The Conceptual Model: Best Practices

The Causal Part of the Conceptual Model

The Appropriate Level of Granularity for Intervention Components

Expressing Moderation in a Conceptual Model

The Pilot Study

Specifying the Optimization Objective

Review of Module 2

Reading for ALL OF Module 2

Week 3 - Introduction to the factorial optimization trial

Importance of the resource management principle

Introduction to the factorial experiment

Fundamental differences between the factorial experiment and the RCT

Why factorial experiments can be so economical

Why the 2^k experiment is so economical

Experimental control in a factorial design

Brief introduction to adaptive interventions

Different interventions, different optimization trial designs

Review of Module 3

Reading for Lessons 1-6

Reading for Lessons 7 and 8

Week 4 - Some conceptual and technical aspects of the factorial experiment

The regression model and coding

Interpretation of interaction effects

Understanding the basics of powering a factorial experiment

Two distinct perspectives on research: Conclusion-priority and decision-priority

Recognizing and dealing with a cluster structure

Review of Module 4

Reading for ALL OF Week 4

Week 5 - Rigorous and responsible conduct of intervention optimization research

Ensuring that all factors can be manipulated independently

Ensuring that all participants are provided with at least the standard of care

What to do if the primary outcome is years in the future

Informed consent in a factorial optimization trial

How to enter an optimization trial in a trial registry

Equipoise in optimization trials

How to avoid contamination

How to guard against protocol deviations

Review of Module 5

Reading for ALL OF Week 5

Week 6 - Completing the optimization phase and identifying your next steps

What it means to conclude the optimization phase of MOST

Introduction to making decisions based on the results of a factorial optimization trial

An example of making decisions based on the results of a factorial optimization trial

Beyond the optimized intervention

Review of Module 6

Reading for ALL of Module 6

Course Review Form

Final Exam

Faculty Icon

Introduction to the Multiphase Optimization Strategy (MOST)
 at 
Coursera 
Faculty details

Linda M Collins
University : New York University
Kate Guastaferro
University : New York University

Introduction to the Multiphase Optimization Strategy (MOST)
 at 
Coursera 
Admission Process

    Important Dates

    May 25, 2024
    Course Commencement Date

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