Duke University - Medical Neuroscience
- Offered byCoursera
Medical Neuroscience at Coursera Overview
Duration | 71 hours |
Start from | Start Now |
Total fee | Free |
Mode of learning | Online |
Difficulty level | Advanced |
Official Website | Explore Free Course  |
Credential | Certificate |
Medical Neuroscience at Coursera Highlights
- Shareable Certificate Earn a Certificate upon completion
- 100% online Start instantly and learn at your own schedule.
- Flexible deadlines Reset deadlines in accordance to your schedule.
- Advanced Level
- Approx. 71 hours to complete
- English Subtitles: Arabic, French, Portuguese (European), Italian, Vietnamese, German, Russian, English, Spanish
Medical Neuroscience at Coursera Course details
- Medical Neuroscience explores the functional organization and neurophysiology of the human central nervous system, while providing a neurobiological framework for understanding human behavior. In this course, you will discover the organization of the neural systems in the brain and spinal cord that mediate sensation, motivate bodily action, and integrate sensorimotor signals with memory, emotion and related faculties of cognition. The overall goal of this course is to provide the foundation for understanding the impairments of sensation, action and cognition that accompany injury, disease or dysfunction in the central nervous system. The course will build upon knowledge acquired through prior studies of cell and molecular biology, general physiology and human anatomy, as we focus primarily on the central nervous system.
- This online course is designed to include all of the core concepts in neurophysiology and clinical neuroanatomy that would be presented in most first-year neuroscience courses in schools of medicine. However, there are some topics (e.g., biological psychiatry) and several learning experiences (e.g., hands-on brain dissection) that we provide in the corresponding course offered in the Duke University School of Medicine on campus that we are not attempting to reproduce in Medical Neuroscience online. Nevertheless, our aim is to faithfully present in scope and rigor a medical school caliber course experience.
- This course comprises six units of content organized into 12 weeks, with an additional week for a comprehensive final exam:
- - Unit 1 Neuroanatomy (weeks 1-2). This unit covers the surface anatomy of the human brain, its internal structure, and the overall organization of sensory and motor systems in the brainstem and spinal cord.
- - Unit 2 Neural signaling (weeks 3-4). This unit addresses the fundamental mechanisms of neuronal excitability, signal generation and propagation, synaptic transmission, post synaptic mechanisms of signal integration, and neural plasticity.
- - Unit 3 Sensory systems (weeks 5-7). Here, you will learn the overall organization and function of the sensory systems that contribute to our sense of self relative to the world around us: somatic sensory systems, proprioception, vision, audition, and balance senses.
- - Unit 4 Motor systems (weeks 8-9). In this unit, we will examine the organization and function of the brain and spinal mechanisms that govern bodily movement.
- - Unit 5 Brain Development (week 10). Next, we turn our attention to the neurobiological mechanisms for building the nervous system in embryonic development and in early postnatal life; we will also consider how the brain changes across the lifespan.
- - Unit 6 Cognition (weeks 11-12). The course concludes with a survey of the association systems of the cerebral hemispheres, with an emphasis on cortical networks that integrate perception, memory and emotion in organizing behavior and planning for the future; we will also consider brain systems for maintaining homeostasis and regulating brain state.
Medical Neuroscience at Coursera Curriculum
Getting Started in Medical Neuroscience
Professor White's Career in Neuroscience
The Scope of Medical Neuroscience
Learning resources for Medical Neuroscience
Your Part!
"Neur-run" with Professor White
Learning Objectives
Your Mentor Team
Preliminary Quiz: Are you ready for Medical Neuroscience?
Professor White's Favorite Places in the Human Brain
Functional Microanatomy of Neurons
Non-Neural Cells of the CNS
Basic Orientation in the Human CNS
Introduction, Learning Objectives and Recommended Reading
Cells of the CNS and Basic Orientation
Neuroanatomy: Surface Anatomy of the Human CNS
Lateral Surface of the Brain
Medial Surface of the Brain
Finding the Central Sulcus
Ventral Surface of the Brain
Building a Digital Brain (Fingers to Gyri)
Surface Anatomy of the Brainstem
Blood Supply to the Brain
Overview of the Cranial Nerves
Overview of the Spinal Nerves
Localizing the Cranial Nerves
Cranial Nerve Function, part 1
Cranial Nerve Function, part 2
Learning Objectives / Recommended Readings
Learning Objectives / Recommended Readings
Cerebral Cortex, Brainstem, and Blood Supply
Cranial and Spinal Nerves
Internal Anatomy of the Brainstem
Cranial Nerve Nuclei, part 1
Cranial Nerve Nuclei, part 2
Cranial Nerve Nuclei, part 3
Cranial Nerve Nuclei, part 4
Internal Anatomy of the Spinal Cord - Gray and White Matter
Internal Anatomy of the Spinal Cord -Longitudinal Organization
Internal Anatomy of the Spinal Cord In Cross Sections
Ventricles
Overview of the Internal Capsule and Deep Gray Matter
Localizing the Internal Capsule and Deep Gray Matter In Brain Slabs
Localizing the Internal Capsule and Deep Gray Matter In Sylvius Atlases
Learning Objectives / Recommended Readings
Learning Objectives / Recommended Readings
Brainstem and Spinal Cord
Forebrain
Neural Signaling: Electrical Excitability and Signal Propagation
Overview of Neuronal Signaling
Ionic Basis of the Resting Membrane Potential, part 1
Ionic Basis of the Resting Membrane Potential, part 2
Ionic Basis of the Action Potential, part 1
Ionic Basis of the Action Potential, part 2
Ionic Basis of the Action Potential, part 3
Molecular Mechanisms of Action Potential Generation, part 1
Molecular Mechanisms of Action Potential Generation, part 2
Propagation of Action Potentials
Learning Objectives / Recommended Readings
Generating and Propagating Electrical Signals
Neural Signaling: Synaptic Transmission and Synaptic Plasticity
Synaptic Transmission, part 1
Synaptic Transmission, part 2
Neurotransmitters, part 1
Neurotransmitters, part 2
Ionotropic Neurotransmitters Receptors, part 1
Ionotropic Neurotransmitters Receptors, part 2
Metabotropic Neurotransmitters Receptors and Postsynaptic Mechanisms
Synaptic Integration
Long-Term Potentiation and Depression, part 1
Long-Term Potentiation and Depression, part 2
Long-Term Potentiation and Depression, part 3
Spike-Timing Dependent synaptic Plasticity
Hebb's Postulate
Learning Objectives / Recommended Readings
Learning Objectives / Recommended Readings
Synaptic Transmission
Synaptic Plasticity
Sensory Systems: General Principles and Somatic Sensation
The Thalamus
Overview and Origins of Cortical Circuits, part 1
Overview and Origins of Cortical Circuits, part 2
General Principles of Sensory Systems, part 1
General Principles of Sensory Systems, part 2
Mechanosensation, part 1
Mechanosensation, part 2
Mechanosensation, part 3
Mechanosensory Pathways, part 1
Mechanosensory Pathways, part 2
Mechanosensory Pathways, part 3
Pain Systems, part 1
Pain Systems, part 2
Pain Systems, part 3
Pain and Temperature Pathways, part 1
Pain and Temperature Pathways, part 2
Learning Objectives / Recommended Readings
Learning Objectives / Recommended Readings
Organizing Principles
Somatic Sensation
Sensory Systems: The Visual System
Basic Structure of the Eye and Retina
Photoreceptors and Phototransduction, part 1
Photoreceptors and Phototransduction, part 2
Ganglion Cell Receptive fields, part 1
Ganglion Cell Receptive fields, part 2
Central Visual Processing, part 1
Central Visual Processing, part 2
Central Visual Processing, part 3
Central Visual Pathways, part 1
Central Visual Pathways, part 2
Visual Field Deficits
Pupillary Light Reflex
Learning Objectives / Recommended Readings
Learning Objectives / Recommended Readings
The Eye
Central Visual Processing
Sensory Systems: Audition, Vestibular Sensation and the Chemical Senses
Peripheral Auditory Mechanisms, part 1
Peripheral Auditory Mechanisms, part 2
Peripheral Auditory Mechanisms, part 3
Central Auditory Processing, part 1
Central Auditory Processing, part 2
Central Auditory Processing, part 3
Peripheral Vestibular Mechanisms, part 1
Peripheral Vestibular Mechanisms, part 2
Peripheral Vestibular Mechanisms, part 3
Central Vestibular Processing, part1
Central Vestibular Processing, part 2
Central Vestibular Processing, part 3
Central Vestibular Processing, part 4
Overview of the Chemical Senses
Olfaction, part 1
Olfaction, part 2
Olfaction, part 3
Olfaction, part 4
Gustation, part1
Gustation, part 2
Gustation, part 3
Trigeminal Chemoreception
Learning Objectives / Recommended Readings
Learning Objectives / Recommended Readings
Learning Objectives / Recommended Readings
Audition
Vestibular Sensation
Chemical Senses
Movement and Motor Control: Lower and Upper Motor Neurons
Overview of the Motor System
Overview of Motor Units
Muscle Spindles and Myotatic Reflexes, part 1
Muscle Spindles and Myotatic Reflexes, part 2
Golgi Tendon Organs
Spindles Versus GTOs, and Withdrawal Reflexes
Central Pattern Generation
Lower Motor Syndrome
Primary Motor Cortex, part 1
Primary Motor Cortex, part 2
Primary Motor Cortex, part 3
Premotor Cortex
Brainstem Upper Motor Neurons
Emotional Motor System
Control of Facial Expressions
Upper Motor Neuron Syndrome
Corticospinal and Corticobulbar Pathways, part 1
Corticospinal and Corticobulbar Pathways, part 2
Learning Objectives / Recommended Readings
Learning Objectives / Recommended Readings
Lower Motor Neuronal Control of Movement
Upper Motor Neuronal Control of Movement
Muscles and Nerves
Overview of Eye Movements
Conjugate Eye Movements
Disconjugate Eye Movements and Eye Movement Physiology
Neural Control of Saccades, part 1
Neural Control of Saccades, part 2
Learning Objectives / Recommended Readings
Eye Movements
Movement and Motor Control: Modulation of Movement
Circuitry of the Basal Ganglia, part 1
Circuitry of the Basal Ganglia, part 2
Circuitry of the Basal Ganglia, part 3
Function of Basal Ganglia Circuitry
Basal Ganglia Function In Normal and Abnormal Movement
Overview of the Cerebellum, part 1
Overview of the Cerebellum, part 2
Cerebellar Circuits, part 1
Cerebellar Circuits, part 2
Cerebellar Circuits, part 3
Cerebellar Function In Normal and Abnormal Movement
Learning Objectives / Recommended Readings
Learning Objectives / Recommended Readings
Modulation of Movement by the Basal Ganglia
Modulation of Movement by the Cerebellum
Functional and Anatomical Divisions of the Visceral Motor System, part 1
Functional and Anatomical Divisions of the Visceral Motor System, part 2
Functional and Anatomical Divisions of the Visceral Motor System, part 3
Central Integration of Visceral Sensory and Motor Signals, part 1
Central Integration of Visceral Sensory and Motor Signals, part 2
Hypothalamus, part 1
Hypothalamus, part 2
Micturition
Learning Objectives / Recommended Readings
Visceral Motor System
The Changing Brain: The Brain Across the Lifespan
Embryological Subdivisions of the Human CNS
Major Forces In Early Brain Development
Neurulation
Formation of the Early CNS
Inductive Signaling In CNS Formation
Proliferation and Migration, part 1
Proliferation and Migration, part 2
Growth Cones
Molecular Signals for Axon Guidance, part 1
Molecular Signals for Axon Guidance, part 2
Neurotrophins
Neurotrophin Receptors and Synapse Formation
Lessons from Studies of Ocular Dominance Columns, part 1
Lessons from Studies of Ocular Dominance Columns, part 2
Lessons from Studies of Orientation and Direction Preference, part 1
Lessons from Studies of Orientation and Direction Preference, part 2
Lessons from Studies of Orientation and Direction Preference, part 3
Neurotrophins In Developmental Plasticity
Brain Development Across the Lifespan, part 1
Brain Development Across the Lifespan, part 2
Functional Plasticity In Cortical Maps
Repair and Regeneration, part 1
Repair and Regeneration, part 2
Learning Objectives / Recommended Readings
Learning Objectives / Recommended Readings
Learning Objectives / Recommended Readings
Early Brain Development
Developmental Plasticity of Neural Circuits In Early Life
Development, Repair and Regeneration Across the Lifespan
Complex Brain Functions: Associational Cortex
Overview of Cognition
Overview of the Associational Cortex
Parietal Associational Cortex, part 1
Parietal Associational Cortex, part 2
Temporal associational Cortex: Visual Recognition
Temporal Associational Cortex: Memory, part 1
Temporal Associational Cortex: Memory, part 2
Temporal Associational Cortex: Language, part 1
Temporal Associational Cortex: Language, part 2
Frontal Associational Cortex: Working Memory
Frontal Associational cortex: Exeutive Function
Learning Objectives / Recommended Reading
Associational Cortex
Complex Brain Functions: Sleep, Emotion and Addiction
Overview of Sleep and Wakefulness
Circadian Rhythms
Brain Waves and Sleep Stages
Neural Circuits That Govern Sleep and Wakefulness, part 1
Neural Circuits That Govern Sleep and Wakefulness, part 2
Sleep Disorders
Amygdala and Hippocampus In the Human Brain
Neurobiology of Emotion, part 1
Neurobiology of Emotion, part 2
Neurobiology of Emotion, part 3
Neurobiology of Emotion, part 4
Reward and Addiction, part 1
Reward and Addiction, part 2
Learning Objectives / Recommended Readings
Learning Objectives / Recommended Readings
Sleep and Wakefulness
Limbic Forebrain, Emotion, and Addiction
Comprehensive Final Exam
Preparing for the Comprehensive Final Exam
Preparation Notes
Example Clinical Case Quiz (UNGRADED, 11 questions)
Comprehensive Final Exam, part 1 (2 cases, 13 questions)
Comprehensive Final Exam, part 2 (2 cases, 7 questions)
Comprehensive Final Exam, part 3 (2 cases, 11 questions)
Comprehensive Final Exam, part 4 (2 cases, 12 questions)
Closing Remarks from Dr. White (05:44)
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