University of Groningen - Why Do We Age? The Molecular Mechanisms of Ageing
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Why Do We Age? The Molecular Mechanisms of Ageing at FutureLearn Overview
Duration | 6 weeks |
Total fee | ₹2,763 |
Mode of learning | Online |
Official Website | Go to Website  |
Credential | Certificate |
Why Do We Age? The Molecular Mechanisms of Ageing at FutureLearn Highlights
- Duration 6 weeks
- Weekly study 4 hours
- 100% online Learn at your own pace
Why Do We Age? The Molecular Mechanisms of Ageing at FutureLearn Course details
- The 'why' and 'how' of ageing has puzzled mankind ever since it questioned its place in the universe.
- However, it was only after infectious diseases became more controlled and reliable food supplies became generally available, that the rapid increase of the average lifespan made science turn its attention to study longevity and ageing.
- To fulfil the desire to live longer and age healthier, it is essential that we better understand the intricate molecular processes that evolve in our body when we age.
- In this free online course, you will study the current concepts and theories of ageing. You will learn about the molecular and cellular processes in ageing. You will explore the cell systems, animal models and advanced experimental methods that we use to study ageing.
- After introducing the main theories and mechanisms of ageing in the first week, we will proceed with a series of in-depth lectures from distinguished researchers working at the European Research Institute for the Biology of Ageing at the University of Groningen. They will present you with a selection of their current research and will explain the fundamental questions they try to answer and the experimental approaches they use for their studies.
- You will learn that ageing starts at the cell level and you will study several phenomena which take place in cells, such as genomic instability, telomere shortening and epigenetic changes.
- By completing this course you will gain insight into the fundamental biology of ageing in various simple and complex organisms, including humans.
Why Do We Age? The Molecular Mechanisms of Ageing at FutureLearn Curriculum
Cellular ageing
Welcome
Why do we study ageing? What is ageing?
Eukaryotic cell structure
Introduction to mechanisms associated with cellular ageing
Glossary on Week 1
Conclusion to Week 1
Chromosomes and ageing
Introduction to Week 2
Using model organisms in ageing research
Mechanism of ageing in yeast - Replicative ageing
Mechanism of ageing in yeast - Telomeres
Aneuploidy, cancer, and ageing
Glossary on Week 1-2
Conclusion to Week 2
Genomic instability and epigenetics
Introduction to Week 3
DNA damage and repair
Telomeres, stem cells, and ageing
Epigenetics and ageing
Mid-course test
Glossary on Week 1-3
Conclusion to Week 3
Stem cells in ageing and rejuvenation
Introduction to Week 4
Single cell sequencing
Haematopoietic stem cells
Regeneration and rejuvenation
Glossary on Week 1-4
Conclusion to Week 4
Health and disease during ageing - molecular aspects
Introduction to Week 5
Decline and disease
Protein aggregation, toxicity, and neurodegeneration
Calorie restriction - health and lifespan
Glossary on Week 1-5
Conclusion to Week 5
Genetics and evolution of ageing
Introduction to Week 6
Genetics of ageing
Evolutionary theories of ageing
Peer review assignment
Glossary on Week 1-6
Conclusion to Week 6 and general conclusion
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